UPTRAVI® (selexipag) Patient Resources

The following resources are designed to help you as you start treatment with UPTRAVI®. You will also find common questions and answers about Janssen CarePath and UPTRAVI®.

Learn more about UPTRAVI®

More information and downloads are available at Uptravi.com.

Dose Adjustment Phase Guide

A guide that highlights important steps and information about titration with UPTRAVI®.

UPTRAVI® Dose Adjustment Phase Guide

UPTRAVI® Prescribing Information

Remember, your healthcare team should always be your first point of contact when you have questions about your health and treatment.

Support from our PAH Companions

The Janssen CarePath PAH Companion* Program provides one-on-one educational support to help you start and stay on your prescribed Janssen medication and resources to help you partner with your healthcare team to better manage your pulmonary arterial hypertension (PAH).

Look to the PAH Companion Program for:

Tools to help you have more productive discussions with your healthcare team

Tips for engaging with your support network (friends, family, and peers)

Ongoing education on managing and living with PAH

Connection with a dedicated PAH Companion through email, phone, and/or text

As part of the program, PAH Companions are ready to answer your questions. Patients who have enrolled can talk to a PAH Companion by calling 866-300-1818, Monday-Friday, 8 AM to 9 PM ET.

*The PAH Companion Program is limited to education about your Janssen therapy, its administration, and/or PAH. It is intended to supplement your understanding of your therapy, and does not provide medical advice or replace a treatment plan from your doctor, nurse, or healthcare team.

Frequently Asked Questions (FAQs)

Janssen CarePath is a program that provides you with support and resources, including benefits verification.

Janssen provides a wide range of support and resources through Janssen CarePath. If you choose to enroll, your Janssen CarePath Care Coordinator will call you to:

  • Help answer your questions about filling your prescription
  • Coordinate with your healthcare provider, insurance company, and specialty pharmacy to help find out if you have coverage for your medicine
  • Inform you of financial assistance programs based on your eligibility

The assistance of Janssen CarePath and our Care Coordinators is available at no cost to patients taking UPTRAVI®.

Enroll today. Call a Janssen CarePath Care Coordinator at 866-228-3546, Monday-Friday, 8 AM to 8 PM ET.

Multilingual phone support is available.

Your Janssen CarePath Care Coordinator may be able to help. Call 866-228-3546, Monday-Friday, 8 AM to 8 PM ET to speak with a Care Coordinator.

Multilingual phone support is available.

To learn about the basic steps of getting a Janssen medicine,
download and review Steps to Getting Your Medicine.

Steps to Getting Your Medicine

A specialty pharmacy is a pharmacy that can ship certain medicines directly to your home. Janssen PAH medicines are available by mail from a specialty pharmacy.

Learn about Working With a Specialty Pharmacy.

A specialty pharmacy will ship UPTRAVI® to your home and may offer additional support services.

Either CVS Specialty or Accredo will call you to discuss financial responsibilities and shipment information.

You or your healthcare provider may have chosen additional support services such as an in-home nurse visit. Your specialty pharmacy will help you to schedule this.

Calls may come from a number you do not recognize. If you miss the call, try to call back as soon as possible to make sure your UPTRAVI® shipment is not delayed.

Your insurance provider will need to gather information about your condition and your treatment before covering UPTRAVI®. Sometimes, all their questions are answered at the time of prescription, but they may also need more information from your healthcare team, including:

  • Diagnostic test results, such as the numbers from your right heart catheterization (RHC)
  • Additional test results, including acute vasoreactivity testing or 6-minute walk distance (6MWD)
  • Details on past treatments you and your healthcare team have tried
  • Information missing from your prescription forms

You may receive additional optional support services, such as an in-home nurse visit before starting UPTRAVI® and specialty pharmacy clinician calls during dose changes.

There are several programs that may help you pay for UPTRAVI®. For information on these programs, call a Janssen CarePath Care Coordinator at 866-228-3546, Monday-Friday, 8 AM to 8 PM ET.

Commercially insured

Janssen CarePath Oral PAH Savings Program for UPTRAVI®

Eligible patients using commercial or private insurance can save on out-of-pocket medication costs for UPTRAVI®. Depending on the health insurance plan, savings may apply toward co-pay, coinsurance or deductible. Eligible patients pay $5 per prescription fill with a $20,000 maximum program benefit per calendar year across all oral PAH therapies in the program. Not valid for patients using Medicare, Medicaid, or other government-funded programs to pay for their medications. Terms expire at the end of each calendar year and may change. There is no income requirement.
See full eligibility requirements.

Government insured or no insurance

If you use a government-funded healthcare program to pay for UPTRAVI® or have no insurance coverage and need help paying for your medication:

Janssen CarePath can provide information about other resources that may be able to help with your out-of-pocket medication costs for UPTRAVI®.

Call a Janssen CarePath Care Coordinator at 866-228-3546 for more information about affordability programs and independent foundations† that may have funding available.

†Independent co-pay assistance foundations have their own rules for eligibility. We cannot guarantee a foundation will help you. We only can refer you to a foundation that supports your disease state. This information is provided as a resource for you. We do not endorse any particular foundation.

There are independent patient advocacy organizations that can provide you with additional support and information:

The Pulmonary Hypertension Association is dedicated to increasing awareness and advocacy by providing information about PAH to both physicians and patients.

Visit their website

The Scleroderma Foundation offers a site for scleroderma patients, caregivers, and family members—dedicated to support, education, and research.

Visit their website
see more

What is UPTRAVI®?

UPTRAVI® (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

UPTRAVI® can help delay (slow down) the progression of your disease and lower your risk of being hospitalized for PAH.

It is not known if UPTRAVI® is safe and effective in children.

IMPORTANT SAFETY INFORMATION

What is the most important information about UPTRAVI®?

Who should not take UPTRAVI®?

  • Do not take UPTRAVI® if you take gemfibrozil because this medicine may affect how UPTRAVI® works and cause side effects

What should I tell my doctor before taking UPTRAVI®?

Tell your doctor if you:

  • Have liver problems
  • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
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What is UPTRAVI®?

UPTRAVI® (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

UPTRAVI® can help delay (slow down) the progression of your disease and lower your risk of being hospitalized for PAH.

It is not known if UPTRAVI® is safe and effective in children.

IMPORTANT SAFETY INFORMATION

What is the most important information about UPTRAVI®?

Who should not take UPTRAVI®?

  • Do not take UPTRAVI® if you take gemfibrozil because this medicine may affect how UPTRAVI® works and cause side effects

What should I tell my doctor before taking UPTRAVI®?

Tell your doctor if you:

  • Have liver problems
  • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
  • Are pregnant or plan to become pregnant. It is not known if UPTRAVI® will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if UPTRAVI® passes into your breast milk. You and your doctor should decide if you will take UPTRAVI® or breastfeed. You should not do both
  • Have any other medical conditions
  • Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements

What are the possible side effects of UPTRAVI®?

The most common side effects are:

  • Headache
  • Diarrhea
  • Jaw pain
  • Nausea
  • Muscle pain
  • Vomiting
  • Pain in arms or legs
  • Temporary reddening of the skin (flushing)
  • Joint pain
  • Low red blood cell count
  • Less appetite than usual
  • Rash

Talk to your doctor if you have a side effect that bothers you or does not go away. These are not all the possible side effects of UPTRAVI®. For more information, ask your doctor or pharmacist.

You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Keep UPTRAVI® and all other medicines away from children.

What other medicines might interact with UPTRAVI®?

  • UPTRAVI® and other medicines may affect each other, causing side effects. Tell your doctor about all the medicines you are taking. Do not start any new medicine until you check with your doctor

How should I take UPTRAVI®?

  • Take UPTRAVI® exactly as your doctor tells you to take it. Usually, your doctor will have you take UPTRAVI® twice a day. Taking UPTRAVI® with food may help you tolerate UPTRAVI® better
  • Swallow UPTRAVI® tablets whole. Do not split, crush, or chew tablets
  • Tell your doctor if you have any form of liver disease. Your doctor may need to change your dose of UPTRAVI®
  • UPTRAVI® is measured in micrograms (mcg). Tablets come in the following strengths: 200, 400, 600, 800, 1000, 1200, 1400, and 1600 mcg

Please read the full Prescribing Information and Patient Product Information for UPTRAVI®.

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What is UPTRAVI®?

+

UPTRAVI® (selexipag) is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1), which is high blood pressure in the arteries of your lungs.

UPTRAVI® can help delay (slow down) the progression of your disease and lower your risk of being hospitalized for PAH.

It is not known if UPTRAVI® is safe and effective in children.

IMPORTANT SAFETY INFORMATION

+

What is the most important information about UPTRAVI®?

Who should not take UPTRAVI®?

  • Do not take UPTRAVI® if you take gemfibrozil because this medicine may affect how UPTRAVI® works and cause side effects

What should I tell my doctor before taking UPTRAVI®?

Tell your doctor if you:

  • Have liver problems
  • Have narrowing of the pulmonary veins (veins in your lungs). This is called pulmonary veno-occlusive disease (PVOD)
  • Are pregnant or plan to become pregnant. It is not known if UPTRAVI® will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if UPTRAVI® passes into your breast milk. You and your doctor should decide if you will take UPTRAVI® or breastfeed. You should not do both
  • Have any other medical conditions
  • Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements

What are the possible side effects of UPTRAVI®?

The most common side effects are:

  • Headache
  • Diarrhea
  • Jaw pain
  • Nausea
  • Muscle pain
  • Vomiting
  • Pain in arms or legs
  • Temporary reddening of the skin (flushing)
  • Joint pain
  • Low red blood cell count
  • Less appetite than usual
  • Rash

Talk to your doctor if you have a side effect that bothers you or does not go away. These are not all the possible side effects of UPTRAVI®. For more information, ask your doctor or pharmacist.

You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Keep UPTRAVI® and all other medicines away from children.

What other medicines might interact with UPTRAVI®?

  • UPTRAVI® and other medicines may affect each other, causing side effects. Tell your doctor about all the medicines you are taking. Do not start any new medicine until you check with your doctor

How should I take UPTRAVI®?

  • Take UPTRAVI® exactly as your doctor tells you to take it. Usually, your doctor will have you take UPTRAVI® twice a day. Taking UPTRAVI® with food may help you tolerate UPTRAVI® better
  • Swallow UPTRAVI® tablets whole. Do not split, crush, or chew tablets
  • Tell your doctor if you have any form of liver disease. Your doctor may need to change your dose of UPTRAVI®
  • UPTRAVI® is measured in micrograms (mcg). Tablets come in the following strengths: 200, 400, 600, 800, 1000, 1200, 1400, and 1600 mcg

Please read the full Prescribing Information and Patient Product Information for UPTRAVI®.

cp-113991v2

Patient insurance benefits investigation and other Janssen CarePath program offerings are provided by third-party service providers for Janssen CarePath, under contract with Johnson & Johnson Health Care Systems Inc. on behalf of Actelion Pharmaceuticals US, Inc., Janssen Biotech, Inc., Janssen Pharmaceuticals, Inc., and Janssen Products, LP (Janssen). The availability of information and assistance may vary based on the Janssen medication, geography and other program differences. Janssen CarePath assists healthcare providers (HCPs) in the determination of whether treatment could be covered by the applicable third-party payer based on coverage guidelines provided by the payer, and patient information provided by the HCP under appropriate authorization following the provider’s exclusive determination of medical necessity. This information and assistance are made available as a convenience to patients, and there is no requirement that patients or HCPs use any Janssen product in exchange for this information or assistance. Janssen assumes no responsibility for and does not guarantee the quality, scope, or availability of the information and assistance provided. The third-party service providers, not Janssen, are responsible for the information and assistance provided under this program. Each HCP and patient is responsible for verifying or confirming any information provided. All claims and other submissions to payers should be in compliance with all applicable requirements.

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Last updated on December 2020.
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